Q301--Zymo Epigenome Sequencing Services
Veterans Affairs · 241-NETWORK CONTRACT OFFICE 01 (36C241)
Capture briefs (a one-page, shareable copy of this page) are part of Pro. The CSV here holds the notice, its timeline and past awards.
Where this opportunity stands
Every notice posted under solicitation 36C24126Q0748 in this department, oldest first.
- Aug 14, 2026 · this noticeSpecial Notice
Next steps for this stage
Standard steps for the notice type; not advice about this buyer.
- Answer the notice: this is when the requirement can still be shaped.
- Contact the contracting officer named on the notice.
- Check who won similar work; they are the likely bidders.
What the notice says
Notice of intent to award a sole source contract. This is not a solicitation. The Department of Veterans Affairs intends to negotiate a sole source contract with: ZYMO RESEARCH CORPORATION 17062 Murphy Avenue Irvine, California 92614, United States MNUYHHMKG8N9 This is not a solicitation. The Department of Veterans Affairs, VA Bedford Healthcare System intends to award a sole source, firm-fixed-price contract to Zymo Research Corporation for Reduced Representation Bisulfite Sequencing (RRBS) services for DNA methylation profiling of 269 post-mortem human choroid plexus tissue samples. Descript… (show all)
ion of Supplies/Services: RRBS services on 269 post-mortem human choroid plexus tissue samples, including sample handling and QC assessment, bisulfite conversion, library preparation and QC assessment, sequencing (~30 million read pairs per sample), and raw data alignment, methylation calling, and genome browser track generation. This requirement supports an ongoing VA research study requiring DNA methylation data from choroid plexus tissue that is directly comparable, at the laboratory-batch level, to an existing dorsolateral prefrontal cortex methylation dataset previously generated in its entirety by Zymo Research Corporation for the same study. Introducing a second laboratory to generate the choroid plexus data would create a vendor-of-origin technical confound that is inseparable from the biological comparison the study is designed to detect, and this confound cannot be reliably resolved through statistical correction after the fact. Zymo Research Corporation is the only vendor that can generate this data using the same laboratory, personnel, and protocol as the existing dataset, thereby preserving the scientific validity of the planned cross-tissue comparison. The contractor will provide the required services. Since the intent is to procure this on a sole source basis, no solicitation will be posted to Contracting Opportunities SAM.gov. A Sources Sought Notice (36C241-26-AP-4037) was previously posted for this requirement; responses received did not identify a source able to meet this specific requirement without introducing the technical confound described above. The authority for this action is RFO 6.103-1, Only One Responsible Source and No Other Supplies or Services Will Satisfy the Agency's Requirements. The NAICS code is 541714. The size standard is 1,000 employees. The PSC is Q301. Interested persons may contact the Contract Specialist by email at [email] regarding this procurement. The determination to conduct a competitive procurement based on responses to this notice is solely within the discretion of the Contracting Officer. Response must be received by 8/21/26 NLT 11:00am EST.
Who won similar work
123 award notices on SAM.gov in the last 24 months. Matched by: Same agency (Veterans Affairs), same product/service code (PSC) Q301.
Single-winner award sizes (123): middle half $275K to $2.9M, median $695K; range $19K to $46.0M.
| Winner | Awards | Value | Last |
|---|---|---|---|
| QUEST DIAGNOSTICS INCORPORATED · $DGX · $9.3B | 20 | $202.4M | Aug 6, 2026 |
| LABORATORY CORPORATION | 15 | $69.7M | Oct 1, 2026 |
| I-2-I Solutions, Inc. | 4 | $2.4M | Oct 2, 2026 |
| WINERGY LLC | 4 | $1.1M | Sep 11, 2025 |
| OREGON HEALTH & SCIENCE UNIVERSITY Portland OR 97239 USA | 3 | $18.7M | Jun 17, 2026 |
| CYTOPATH BIOPSY LAB INC | 3 | $1.5M | Sep 22, 2026 |
| VERACYTE LABS SD CORPORATION · $VCYT · $361.1M | 3 | $859K | Jun 2, 2026 |
| UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE Seattle WA 98195 USA | 2 | $9.7M | Dec 2, 2025 |
| BECKMAN COULTER, INC | 2 | $5.0M | Nov 28, 2025 |
| ROCHE DIAGNOSTICS CORPORATION | 2 | $2.6M | Nov 13, 2025 |
Value counts single-winner awards. "Shared" awards are multiple-award contracts that list every winner with the same total ceiling; that ceiling is not one company's win, so it is not added in. Revenue next to a ticker is the company's last annual revenue from its 10-K.
- $DGX reported $9.3B revenue in FY2025. The median single-winner award in these 123 past awards, $695K, is under 0.1% of that. 10-K
- $VCYT reported $361.1M revenue in FY2025. The median single-winner award in these 123 past awards, $695K, is 0.2% of that. 10-K
One award's total value against one year of revenue; many awards are paid over several years.
- Oct 6, 2026MINNESOTA VALLEY TESTING LABORATORIES, INC.$452KQ301--Water Quality Laboratory Testing ServicesNo listed company matched (Materiality N/A)
- Oct 2, 2026I-2-I Solutions, Inc.$1.7MQ301--Legionella Testing VISN 6No listed company matched (Materiality N/A)
- Oct 1, 2026BITSCOPIC INC$475KSoftware License - Oncology Informatics Module for PraediGene Software PlatformNo listed company matched (Materiality N/A)
- Oct 1, 2026LABORATORY CORPORATION$1.3MQ301--CYTOPATHOLOGY AND NEXT GENERATION SEQUENCING TESTING SERVICESNo listed company matched (Materiality N/A)
- Sep 29, 2026LABORATORY CORPORATION$7.3MAward Notice - Reference Lab Testing ServicesNo listed company matched (Materiality N/A)
- Sep 25, 2026THE JOHNS HOPKINS UNIVERSITY Baltimore MD 21218 USA$624KSpecialized Biomarker Lab for TRACTSNo listed company matched (Materiality N/A)
- Sep 22, 2026CYTOPATH BIOPSY LAB INC$1.0MQ301-- Molecular Thyroid TestingNo listed company matched (Materiality N/A)
- Sep 16, 2026EXOSOME DIAGNOSTICS INC$1.1MQ301--Base Year | 36C259-26-AP-1918 | Prostate Testing Non-Invasive | VISN ContractMateriality: 0.09% of $TECH revenue (Low) SEC
- Sep 8, 2026UPMC Presbyterian Shadyside Pittsburgh PA 15213 USA$681KReference Laboratory TestingNo listed company matched (Materiality N/A)
- Sep 1, 2026VETERANS COMMAND, LLC$132KQ301-- Transcription Services Washington DC VAMCNo listed company matched (Materiality N/A)
Materiality: one award's value as a share of the winner's revenue over the latest 12 months in its SEC filings (or its last fiscal year, as noted when you point at it). Low under 1%, Medium 1 to 5%, High 5% or more. Many awards are paid over several years, so this overstates a single year's share.
Competitive landscape
For the 8 most frequent past winners above. Lobbying is matched by the company's exact name or exact ticker; agencies are as named on the filings.
- 0 of these past winners lobbied Veterans Affairs, Dept of (VA) since 2024 (0 filings)
- 0 of their lobbyists list a past Veterans Affairs, Dept of (VA) job
- $22K from their corporate PACs since 2024 to members of House Committee on Appropriations, House Committee on Veterans' Affairs, Senate Committee on Appropriations, Senate Committee on Veterans' Affairs
- 0 foreign-agent (FARA) registrations
Policy around it
Bills the past winners named while lobbying this agency's issues, rules from the department, and executive orders that name the agency, last 12 months.
- 0 bills named on the past winners' lobbying filings
- 25 rules from the department in the last 12 months
- 0 executive orders naming the agency in the last 12 months
Market
For past winners matched exactly to a listed company. Insider trades are open-market buys and sells (Form 4) in the last 90 days, shown as facts; our own study found insiders do not reliably buy ahead of awards. A sale marked 10b5-1 was made under a trading plan set up in advance.
- 2 of the past winners are listed companies
- 0 insider buys and 5 insider sells at them in the last 90 days
Sources: SAM.gov notices and award notices; Senate LDA lobbying filings; FEC filings; FARA; Federal Register; congress.gov; SEC Form 4. Every row above links to its record.
Companies are matched to tickers by exact name only. A company we could not match shows no market rows; that is a miss, not a finding.