ARPA-H Comprehensive Organ System Modeling in Outer Space (COSMOS) Innovative Solutions Opening
National Institutes of Health · ADVANCED RESEARCH PROJECTS AGENCY FOR HEALTH (ARPA-H)
Capture briefs (a one-page, shareable copy of this page) are part of Pro. The CSV here holds the notice, its timeline and past awards.
Where this opportunity stands
Every notice posted under solicitation ARPA-H-SOL-26-165 in this department, oldest first.
Next steps for this stage
Standard steps for the notice type; not advice about this buyer.
- Decide bid or no bid before the response deadline.
- Look at the past winners for likely competitors and teaming partners.
- Follow the opportunity to hear about amendments and the award.
What the notice says
The Advanced Research Projects Agency for Health (ARPA-H) Comprehensive Organ System Modeling in Outer Space (COSMOS) Initiative aims to definitively prove or disprove if exposure to microgravity in Low Earth Orbit (LEO) truly accelerates tissue aging across brain, cardiac, uterine, and kidney tissue types and across several adult age brackets. Provided Tissue Aging Rate in Space (TARIS) exceeds Tissue Aging Rate on Earth (TAROE) at a rate that exceeds the on Earth breakeven cost for new drug R&D, COSMOS will create a first-in-class platform for fully autonomous, high-throughput drug screening… (show all)
in LEO that would be more cost effective and faster than new drug R&D on Earth. ARPA-H anticipates multiple Other Transaction awards resulting from this announcement. Interested parties are invited to download and review the attached COSMOS Innovative Solutions Opening (ISO) ARPA-H-SOL-26-165 Amendment 01 � 17 September 2026: This amendment includes updated hyperlinks and information on the updated Solutions summary portal. Questions and Answers � 21 September 2026: This Q&A is provided for informational purposes only and does not amend the solicitation. All other questions are due by 23 September 2026 at 5:00PM ET. Amendment 02 � 23 September 2026: This amendment includes updates to Section 3, COSMOS Details; Section 4, Mandatory Experimental Design; as well as Correction to Figure 2. Questions and Answers � 25 September 2026: This Q&A is provided for informational purposes only and does not amend the solicitation. Amendment 03 � 07 October 2026: This amendment extends the submission time, now due 07 October 2026, 5:00pm ET.
Who won similar work
15 award notices on SAM.gov in the last 24 months. Match: Same agency (National Institutes of Health), same NAICS 541714.
| Winner | Awards | Value | Last |
|---|---|---|---|
| UNIVERSITY OF MARYLAND, BALTIMORE Baltimore MD 21201 USA | 2 | $30.8M | Aug 6, 2026 |
| FISHER BIOSERVICES INC · $TMO | 1 | $100.0M | Jan 21, 2025 |
| Coriell Institute for Medical Research, Inc. | 1 | $48.3M | Aug 1, 2025 |
| THE MCLEAN HOSPITAL CORPORATION | 1 | $34.9M | Nov 21, 2025 |
| UNIVERSITY OF MIAMI Coral Gables FL 33146 USA | 1 | $26.6M | Nov 21, 2025 |
| LA JOLLA INSTITUTE FOR IMMUNOLOGY La Jolla CA 92037 USA | 1 | $24.3M | Mar 16, 2026 |
| UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION Pittsburgh PA 15260 USA | 1 | $19.9M | Nov 21, 2025 |
| ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI New York NY 10029 USA | 1 | $18.5M | Nov 21, 2025 |
| Greater Los Angeles Veterans Research and Education Foundation Los Angeles CA 90073 USA | 1 | $17.7M | Nov 21, 2025 |
| THE BROAD INSTITUTE, INC | 1 | $215K | Sep 29, 2026 |
Value counts single-winner awards. "Shared" awards are multiple-award contracts that list every winner with the same total ceiling; that ceiling is not one company's win, so it is not added in.
- Sep 29, 2026THE BROAD INSTITUTE, INC$215KWhole genome sequencing for investigation of age-related chronic disease in HANDLS participants
- Aug 6, 2026UNIVERSITY OF MARYLAND, BALTIMORE Baltimore MD 21201 USA$552KRNCP PORTFOLIO-WIDE DOSIMETRY VERIFICATION SERVICES
- Mar 16, 2026LA JOLLA INSTITUTE FOR IMMUNOLOGY La Jolla CA 92037 USA$24.3MIMMUNE EPITOPE DATABASE AND ANALYSIS PROGRAM
- Nov 21, 2025Greater Los Angeles Veterans Research and Education Foundation Los Angeles CA 90073 USA$17.7MA--NIH NeuroBioBank Brain and Tissue Repository
- Nov 21, 2025THE UNIVERSITY OF IOWA Iowa City IA 52242 USA$13.1M (shared ceiling)A--NIH NeuroBioBank Brain and Tissue Repository
- Nov 21, 2025IOWA UNIV OF Iowa City IA 52242 USA$13.1M (shared ceiling)A--NIH NeuroBioBank Brain and Tissue Repository
- Nov 21, 2025UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION Pittsburgh PA 15260 USA$19.9MA--NIH NeuroBioBank Brain and Tissue Repository
- Nov 21, 2025UNIVERSITY OF MIAMI Coral Gables FL 33146 USA$26.6MA--NIH NeuroBioBank Brain and Tissue Repository
- Nov 21, 2025UNIVERSITY OF MARYLAND, BALTIMORE Baltimore MD 21201 USA$30.3MA--NIH NeuroBioBank Brain and Tissue Repository
- Nov 21, 2025THE MCLEAN HOSPITAL CORPORATION$34.9MA--NIH NeuroBioBank Brain and Tissue Repository
Competitive landscape
For the 8 most frequent past winners above. Lobbying is matched by the company's exact name or exact ticker; agencies are as named on the filings.
- 1 of these past winners lobbied Natl Institutes of Health (NIH) since 2024 (7 filings)
- 0 of their lobbyists list a past Natl Institutes of Health (NIH) job
- $64K from their corporate PACs since 2024 to members of House Committee on Appropriations, House Committee on Energy and Commerce, Senate Committee on Appropriations, Senate Committee on Health, Education, Labor, and Pensions
- 0 foreign-agent (FARA) registrations
Policy around it
Bills the past winners named while lobbying this agency's issues, rules from the department, and executive orders that name the agency, last 12 months.
- 8 bills named on the past winners' lobbying filings
- 0 rules from the department in the last 12 months
- 0 executive orders naming the agency in the last 12 months
Market
For past winners matched exactly to a listed company. Insider trades are open-market buys and sells (Form 4) in the last 90 days, shown as facts; our own study found insiders do not reliably buy ahead of awards.
- 1 of the past winners are listed companies
- 0 insider buys and 7 insider sells at them in the last 90 days
Sources: SAM.gov notices and award notices; Senate LDA lobbying filings; FEC filings; FARA; Federal Register; congress.gov; SEC Form 4. Every row above links to its record.
Companies are matched to tickers by exact name only. A company we could not match shows no market rows; that is a miss, not a finding.